| Medicine | |
| Alchohol Interaction | Taking Domperidone+Flunarizine+Paracetamol / Acetaminophen with alcohol can cause liver damage. |
| Pregnancy Interaction | Zerograin-Plus Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
| Lactation Interaction | No information is available on the use of Zerograin-Plus Tablet during lactation. Please consult your doctor. |
| Common Side Effect | Weight gain, Drowsiness, Dryness in mouth. |
| How to Use | Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zerograin-Plus Tablet is to be taken empty stomach. |
| Driving | Zerograin-Plus Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive. |
| Kidney | Zerograin-Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Zerograin-Plus Tablet may not be needed in these patients. Please consult your doctor. |
| Liver | Zerograin-Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Zerograin-Plus Tablet may be needed. Please consult your doctor.However, the use of Zerograin-Plus Tablet is not recommended in patients with severe liver disease and active liver disease. |
| Mechanism of action | Zerograin-Plus Tablet is a combination of three medicines: Domperidone, Flunarizine and Paracetamol / Acetaminophen which prevent migraine accompanied by nausea/vomiting. Domperidone is an antiemetic and prokinetic which blocks the action of a dopamine (a chemical messenger) in the brain which causes nausea and vomiting. Flunarizine is a calcium channel blocker which works by preventing the narrowing of blood vessels in the head thereby preventing migraine headache. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain. |
Tags: Zerograin-Plus Tablet