| Medicine | |
| Alchohol Interaction | Taking Guaifenesin+Bromhexine+Chlorpheniramine+Paracetamol / Acetaminophen+Ephedrine with alcohol can cause liver damage. |
| Pregnancy Interaction | Koff GO Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
| Lactation Interaction | No information is available on the use of Koff GO Tablet during lactation. Please consult your doctor. |
| Common Side Effect | Nausea, Diarrhoea, Stomach pain, Vomiting, Rash, Urticaria, Allergic reaction, Sleepiness, Dizziness, Headache, Anxiety, Restlessness, Insomnia (difficulty in sleeping), Increased heart rate. |
| How to Use | Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Koff GO Tablet may be taken with or without food, but it is better to take it at a fixed time.Take it with food if stomach upset occurs. |
| Driving | Koff GO Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive. |
| Kidney | Koff GO Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Koff GO Tablet may not be needed in these patients. Please consult your doctor.Use of Koff GO Tablet may cause excessive sleepiness in patients with end stage kidney disease. |
| Liver | Koff GO Tablet should be used with caution in patients with liver disease. Dose adjustment of Koff GO Tablet may be needed. Please consult your doctor.However, the use of Koff GO Tablet is not recommended in patients with severe liver disease and active liver disease. |
| Mechanism of action | Koff GO Tablet is a combination of five medicines: Guaifenesin, Bromhexine, Chlorpheniramine, Paracetamol / Acetaminophen and Ephedrine.tGuaifenesin and Bromhexine help in the removal of mucus (phlegm) from the airways. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Paracetamol / Acetaminophen is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Ephedrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. |
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