| Medicine | |
| Alchohol Interaction | Taking Chlorthalidone with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. |
| Pregnancy Interaction | Trilosar 12.5 mg Tablet is unsafe to use during pregnancy.There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor. |
| Lactation Interaction | Trilosar 12.5 mg Tablet is probably safe to use during lactation. \nLimited human data suggests that the drug does not represent a significant risk to the baby. |
| Common Side Effect | Nausea, Altered taste, Stomach upset, Diarrhoea, Dizziness, Flushing (sense of warmth in the face, ears, neck and trunk), Headache, Increased blood uric acid, Increased blood lipid level, Decreased sodium level in blood, Decreased magnesium level in blood, Decreased blood pressure, Numbness of extremity. |
| How to Use | Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trilosar 12.5 mg Tablet is to be taken with food. |
| Driving | Do not drive unless you are feeling well.Trilosar 12.5 mg Tablet may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive. |
| Kidney | Trilosar 12.5 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Trilosar 12.5 mg Tablet may be needed. Please consult your doctor.Use of Trilosar 12.5 mg Tablet is not recommended in these patients. |
| Liver | Trilosar 12.5 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Trilosar 12.5 mg Tablet may be needed. Please consult your doctor.Use of Trilosar 12.5 mg Tablet is not recommended in patients with severe liver disease. |
| Mechanism of action | Trilosar 12.5 mg Tablet is a combination of three medicines: Losartan, Amlodipine and Chlorthalidone. Losartan is an angiotensin receptor blocker (ARB) and Amlodipine is a calcium channel blocker (CCB). They work by widening and relaxing the blood vessels, thereby lowering blood pressure. Chlorthalidone is a diuretic which removes extra water and certain electrolytes from the body through urine. Over time it also works by relaxing blood vessels and improving blood flow. |
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