Medicine | |
Alchohol Interaction | Taking Propranolol with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. |
Pregnancy Interaction | Nigrain Forte Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
Lactation Interaction | No information is available on the use of Nigrain Forte Tablet during lactation. Please consult your doctor. |
Common Side Effect | Weight gain, Slow heart rate, Tiredness, Depression, Drowsiness, Abnormal dreams, Cold extremities. |
How to Use | Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nigrain Forte Tablet is to be taken empty stomach. |
Driving | Do not drive unless you are feeling well.Nigrain Forte Tablet may cause visual disturbances, hallucinations, fatigue, mental confusion, dizziness or tiredness. This may affect your driving ability. |
Kidney | Nigrain Forte Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nigrain Forte Tablet may not be needed in these patients. Please consult your doctor. |
Liver | Nigrain Forte Tablet should be used with caution in patients with liver disease. Dose adjustment of Nigrain Forte Tablet may be needed. Please consult your doctor.Regular monitoring of blood pressure is advisable for dose adjustment. |
Mechanism of action | Nigrain Forte Tablet is a combination of two medicines: Propranolol and Flunarizine which prevent migraine.tPropranolol is a beta blocker and Flunarizine is a calcium channel blocker. They work by stabilizing the reactive nerve cells and increasing the threshold to migraine activation. They also inhibit cortical spreading depression (CSD- electric waves that move across the brain and cause pain and inflammation). |
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