Medicine | |
Alchohol Interaction | Taking Bromhexine+Chlorpheniramine+Guaifenesin+Phenylephrine+Paracetamol / Acetaminophen with alcohol can cause liver damage. |
Pregnancy Interaction | Labocof 4mg/4mg/50mg/5mg/450mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
Lactation Interaction | No information is available on the use of Labocof 4mg/4mg/50mg/5mg/450mg Tablet during lactation. Please consult your doctor. |
Common Side Effect | Nausea, Vomiting, Diarrhoea, Bloating, Stomach pain, Indigestion, Loss of appetite, Dizziness, Headache, Sweating, Sleepiness, Rash, Insomnia (difficulty in sleeping), Allergic reaction. |
How to Use | Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Labocof 4mg/4mg/50mg/5mg/450mg Tablet may be taken with or without food, but it is better to take it at a fixed time.Take it with food if stomach upset occurs. |
Driving | Labocof 4mg/4mg/50mg/5mg/450mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive. |
Kidney | Labocof 4mg/4mg/50mg/5mg/450mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Labocof 4mg/4mg/50mg/5mg/450mg Tablet may not be needed in these patients. Please consult your doctor.Use of Labocof 4mg/4mg/50mg/5mg/450mg Tablet may cause excessive sleepiness in patients with end stage kidney disease. |
Liver | Labocof 4mg/4mg/50mg/5mg/450mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Labocof 4mg/4mg/50mg/5mg/450mg Tablet may be needed. Please consult your doctor.However, the use of Labocof 4mg/4mg/50mg/5mg/450mg Tablet is not recommended in patients with severe liver disease and active liver disease. |
Mechanism of action | Labocof 4mg/4mg/50mg/5mg/450mg Tablet is a combination of five medicines: Bromhexine, chlorpheniramine, guaifenesin, phenylephrine and paracetamol which relieve common cold symptoms. Bromhexine is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Guaifenesin is an expectorant which decreases the stickiness of mucus (phlegm), further helping in its removal from the airways. Phenylephrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. |