Medicine | |
Alchohol Interaction | Taking Voglibose with alcohol reduce the blood sugar levels in diabetic patients. |
Pregnancy Interaction | Trivolib Forte 1 Tablet ER may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
Lactation Interaction | Trivolib Forte 1 Tablet ER is probably safe to use during lactation. \nLimited human data suggests that the drug does not represent a significant risk to the baby. |
Common Side Effect | Hypoglycemia (low blood sugar level), Nausea, Diarrhoea, Altered taste, Flatulence, Stomach pain, Headache, Skin rash, Respiratory tract infection. |
How to Use | Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trivolib Forte 1 Tablet ER is to be taken with food.Trivolib Forte 1 Tablet ER may cause stomach upset if taken on empty stomach. |
Driving | Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive. |
Kidney | Trivolib Forte 1 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Trivolib Forte 1 Tablet ER may be needed. Please consult your doctor.Use of Trivolib Forte 1 Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine. |
Liver | Trivolib Forte 1 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Trivolib Forte 1 Tablet ER may be needed. Please consult your doctor.Trivolib Forte 1 Tablet ER is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease. |
Mechanism of action | Trivolib Forte 1 Tablet ER is a combination of three antidiabetic medicines: Glimepiride, metformin and voglibose. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide which lowers glucose production in the liver, delays glucose absorption from intestines and increases the body's sensitivity to insulin. Voglibose is an alpha-glucosidase inhibitor which prevents breakdown of complex sugars into simple sugars such as glucose. This prevents blood glucose from rising very high after meals. |