Description
| Medicine | |
| Alchohol Interaction | Duotop Tablet may cause excessive drowsiness and calmness with alcohol. |
| Pregnancy Interaction | Duotop Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
| Lactation Interaction | Duotop Tablet is probably unsafe to use during lactation. \nLimited human data suggest that the drug could represent a significant risk to the baby. |
| Common Side Effect | Nausea, Constipation, Headache, Insomnia (difficulty in sleeping), Ejaculation disorder, Erectile dysfunction, Low sexual desire. |
| How to Use | Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duotop Tablet may be taken with or without food, but it is better to take it at a fixed time. |
| Driving | Duotop Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive. |
| Kidney | Duotop Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Duotop Tablet may be needed. Please consult your doctor.Dose adjustment is not recommended in patients with mild and moderate kidney disease. |
| Liver | Duotop Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor. |
| Mechanism of action | Duotop Tablet is a combination of two medicines: Duloxetine and methylcobalamin. Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) which works by increasing the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibres and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves). |
Tags: Duotop Tablet