Description
| Medicine | |
| Alchohol Interaction | Taking rosiglitazone with alcohol may affect blood glucose levels in patients with diabetes. |
| Pregnancy Interaction | DIABETROL 3D 5 MG/500 MG/15 MG TABLET may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
| Lactation Interaction | No information is available on the use of DIABETROL 3D 5 MG/500 MG/15 MG TABLET during lactation. Please consult your doctor. |
| Common Side Effect | Hypoglycemia (low blood sugar level), Nausea, Altered taste, Diarrhoea, Stomach pain, Headache, Edema (swelling), Weight gain, Blurred vision, Bone fracture, Respiratory tract infection. |
| How to Use | Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DIABETROL 3D 5 MG/500 MG/15 MG TABLET is to be taken with food.DIABETROL 3D 5 MG/500 MG/15 MG TABLET may cause stomach upset if taken empty stomach. |
| Driving | Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive. |
| Kidney | DIABETROL 3D 5 MG/500 MG/15 MG TABLET is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor. |
| Liver | DIABETROL 3D 5 MG/500 MG/15 MG TABLET should be used with caution in patients with liver disease. Dose adjustment of DIABETROL 3D 5 MG/500 MG/15 MG TABLET may be needed. Please consult your doctor.Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. |
| Mechanism of action | DIABETROL 3D 5 MG/500 MG/15 MG TABLET is a combination of three antidiabetic medicines: Glibenclamide, Metformin and Rosiglitazone. tThey work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Rosiglitazone is a thiazolidinedione which further increases insulin sensitivity. Glibenclamide, Metformin and Rosiglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Rosiglitazone is a thiazolidinedione which further increases insulin sensitivity. |