Description
| Medicine | |
| Alchohol Interaction | Amicobal 10mg/1500mcg Tablet may cause excessive drowsiness and calmness with alcohol. |
| Pregnancy Interaction | Amicobal 10mg/1500mcg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
| Lactation Interaction | Amicobal 10mg/1500mcg Tablet is probably unsafe to use during lactation. \nLimited human data suggest that the drug could represent a significant risk to the baby. |
| Common Side Effect | Constipation, Difficulty in urination, Weight gain, Dryness in mouth, Orthostatic hypotension (sudden lowering of blood pressure on standing), Drowsiness, Blurred vision, Increased heart rate. |
| How to Use | Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amicobal 10mg/1500mcg Tablet may be taken with or without food, but it is better to take it at a fixed time.Take with food if it causes stomach upset |
| Driving | Do not drive unless you are feeling well.Amicobal 10mg/1500mcg Tablet may impair your alertness which may affect your ability to drive. |
| Kidney | Amicobal 10mg/1500mcg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amicobal 10mg/1500mcg Tablet may not be needed in these patients. Please consult your doctor. |
| Liver | Amicobal 10mg/1500mcg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amicobal 10mg/1500mcg Tablet may be needed. Please consult your doctor.Use of Amicobal 10mg/1500mcg Tablet is not recommended in patients with severe liver disease. |
| Mechanism of action | Amicobal 10mg/1500mcg Tablet is a combination of two medicines: Amitriptyline and methylcobalamin. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibres and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves). |