|Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
|Unknown. Human and animal studies are not available. Please consult your doctor.
|No information is available on the use of Afoglip M 500 Tablet during lactation. Please consult your doctor.
|Common Side Effect
|Diarrhoea, Nausea, Vomiting, Stomach upset, Headache, Nasal congestion, Sore throat, Respiratory tract infection, Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea.
|How to Use
|Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afoglip M 500 Tablet is to be taken with food.Afoglip M 500 Tablet may cause stomach upset if taken on empty stomach.
|Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
|Afoglip M 500 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Afoglip M 500 Tablet may be needed. Please consult your doctor.Use of Afoglip M 500 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
|Afoglip M 500 Tablet should be used with caution in patients with liver disease. Dose adjustment of Afoglip M 500 Tablet may be needed. Please consult your doctor.Afoglip M 500 Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
|Mechanism of action
|Afoglip M 500 Tablet is a combination of two antidiabetic medicines: Metformin and Teneligliptin. Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.
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